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| Introduction | ||||
| Haematopoiesis
(blood formation) has long served as a model process for studying stem
cells and represents the best characterised adult stem cell system with
functional assays and purification strategies for a plethora of
precursors ranging from the pluripotent haematopoietic stem cell (HSC)
via multipotent and unipotent progenitors to at least 14 distinct
mature cell types. Transcriptional control is a key factor
controlling haematopoiesis. Our current understanding of mouse haematopoiesis is depicted on the figure on the right. |
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| Main features of this server | ||||
| BloodExpress
integrates 271
individual microarray experiments derived from 15 distinct studies done on most characterised mouse blood
cell types. Gene expression information has been discretised
to absent/present/unknown calls. Briefly, on this server you can do: • Gene-centric searches to find out where your gene of interest is expressed, and what other genes follow the same (or a similar) pattern of expression ('guilt by association') • Cell-centric searches to find out what genes are expressed in specific cell types/studies and not others | ||||
| Citing this database | ||||
| Miranda-Saavedra, D. et al (2008) BloodExpress: A Database of Gene Expression in Mouse Haematopoiesis. Nucleic Acids Research Nov 4 [Epub ahead of print] link | ||||
| Contact the BloodExpress administrator | ||||
| Diego Miranda-Saavedra Haematopoietic Stem Cell Laboratory Cambridge Institute for Medical Research Wellcome Trust/MRC Building Hills Rd, Cambridge CB2 0XY United Kingdom web / email | ||||