CoMoDis - (Human Ensembl v37)

Run CoMoDis



Example Files




Run CoMoDis.

This tool is designed to extract regions of sequence surrounding conserved transcription factor binding sites (TFBSs) of your choice within a given distance of a set of 'interesting' genes.

This version of CoMoDis is based on the UCSC alignments of:

  • Human (NCBI35/hg17) [Reference genome]
  • Mouse (NCBI33/mm5)

You can choose one of three TFBS datasets. These are:

In-house sites are consensus binding sites represented IUPAC codes taken from the literature, experimental work or other databases.

Xie et. al. (2005) Nature 434:338-345 these sites are over-represented consensus sequences that are conserved (human, dog, mouse and rat) in the promoters of RefSeq genes.

Ettwiller et. al. (2005) Genome Biology 6:R104 these sites are over-represented consensus sequences that conserved (human and mouse) in the promoters of Ensembl genes.

TRANSFAC v8.3 sites have been downloaded from the UCSC database and are conserved between human, mouse and rat genomes.

Select TFBS dataset:

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Last modified: Thursday 15 February 2007.